Polymer PEG Derivatives has been used in medicine, materials, chemical and other fields.
At present, most of the polyethylene glycol compounds supplied on the market are polymers formed by the polymerization of ethylene glycol. The molecular weight of polymer PEG compounds is uncertain, and distributed in a certain range. It will be difficult to quantify the modified compounds in practice because of disperse molecular weight. In addition, it is very difficult to separate and purify polyethylene glycol compounds because of their similar structure, so it is particularly important to design a synthesis method of monodisperse polyethylene glycol(PEG) derivatives.
Monodisperse polyethylene glycol(PEG) molecular weight is fixed. It can not be obtained by polymerization. It must be by the appropriate reaction of the basic polyethylene glycol fragment.
At present, the monodisperse custom synthesis PEG is difficult, the literature is less reported and poor, and the price of monodisperse polyethylene glycol sold on the market is also expensive. For the above reasons, an economical and efficient monodisperse polyethylene glycol synthesis method need to be designed, which can provide with higher quality and lower price.